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doi: 10.1152/ajprenal.00260.2018, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 36.Nasu K, Kawakami T, Shinohara A, Sakamoto T, Nangaku M

The prevalence of this disease is rising dramatically in the world, and the global prevalence of diabetes is about 8.8% (415 million) in 2015 [2]

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Oxidative stress in Parkinson's disease: a systematic review and meta-analysis

In a mouse model of LPS-induced liver injury, API (100, 200 mg/kg) exhibited significant hepatoprotective effects by inhibiting NF-B and MAPK signaling cascades, enhancing both enzymatic and non-enzymatic antioxidant levels, and effectively reducing oxidative stress, neutrophil infiltration and inflammatory responses ( D-Galactosamine (D-GalN) is an amino sugar compound that specifically interferes with RNA and protein synthesis in hepatocytes, leading to apoptosis and necrosis, as well as severe hepatitis and liver dysfunction (Maes et al., 2016)

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