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DOI: 10.1192/bjo.2022.563 Horowitz MA, Buckman JEJ, Saunders R, et al

To address copper-dependent toxicity in WD in human liver cells, we reanalysed the RNA sequencing data (GSE107323) [2], validated gene expression signatures and functionally addressed our findings in the HepG2 ATP7B knockout (ATP7B-KO) model [7]

Immunotherapy represents an emerging disease treatment strategy in the clinical validation phase, aiming for early intervention to slow pathological progression

Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling

Gross MI, Demo SD, Dennison JB, Chen L, Chernov-Rogan T, Goyal B, et al
