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Description
Claudins and epithelial paracellular transport

Bielack SS, Soussain C, Fox CP, Houillier C, Murciano T, Osborne W, Zinzani PL, Rizzari C, Schwartz S (2024) A European consensus recommendation on the management of delayed methotrexate elimination: supportive measures, leucovorin rescue and glucarpidase treatment

As a clinical necessity
Dr Jastreboff notes that mild to moderate gastrointestinal side effects are possible

Compounds that were selective toward the closely related APN and that exhibited sub-M affinity were identified

doi: 10.3390/CANCERS14143525 [DOI] [PMC free article] [PubMed] [Google Scholar] 191
