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Preclinical studies Recently, it was suggested that targeting energy metabolism by a modified diet supplemented with 25% 8- and 10-carbon MCTs may be considered as part of a multimodal treatment regimen to improve the efficacy of neuroblastoma anticancer therapy in CD-1 Nu mouse model (Aminzadeh-Gohari et al

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Temporary energy buffering is also linked to the activation of mitochondrial respiration, which forms a creatinephosphocreatine shuttle called the spatial energy buffer [46]