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Description
Efferocytosis of alveolar macrophages is essential for alleviating ALI as it prevents excessive inflammatory responses and assists in the reconstruction of lung tissue to attenuate lung injury

Tissue is first embedded in a low melt agarose in PBS 141

Effect of pH, type of buffer and liposome encapsulation
This isoquinoline alkaloid usually accumulates in mitochondria and partially inhibits complex I, which raises the AMP: ATP ratio and transiently activates AMP-activated protein kinase (AMPK)
This takes about four half-lives of the drug

10.1172/jci26373 158 ZambonF.CherubiniM.FernandesH
