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Description
408 Additionally, ZnT9 is the coactivator of -catenin-mediated gene transcription, 409,410 which serves as the critical event in the Wnt signaling pathway and the development and progression of colon cancer

This helps it reach the cells
They may be secreted unchanged for further metabolism, principally within the liver

Psychiatry 20 (4), 440446
doi: 10.1016/j.freeradbiomed.2021.10.028, 24
doi: 10.1053/j.gastro.2010.08.006