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Its GIP receptor binding is actually the most potent of the three pathways, with an EC50 of 0.0643 nM compared to 0.775 nM for GLP-1

Specifically, genes associated with energy metabolism, cell proliferation, muscle myosin isoforms, as well as immune functions were found to be altered

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Although only three anti-estrogenic substances banned by WADA were identified in this study, clomiphene, tamoxifen, and raloxifene, it should be remembered that other banned substances from the S4.2 group, such as bazedoxifene, cyclofenil, fulvestrant, ospemifene, or toremifene, may also be present in illegal samples purchased by athletes (Okano et al., 2022)