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RanGAP1, the only GAP for Ran demonstrated up till now, is located around the nuclear envelope by association with RanBP2 in interphase cells [47], while PlexinB1, a transmembrane receptor, localises predominantly to the plasma membrane

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Common probes used for selective Oxy-Cys proteomics analysis and click chemistry approaches are shown in Figure 5

Programmed death-ligand 1 (PD-L1), encoded by the CD274 gene and belonging to the B7 family of immune checkpoint proteins, is frequently overexpressed in the tumor microenvironment, facilitating immune evasion