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The primary function of BH4 is as a cofactor for monooxygenase enzymes [78]
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Altered circadian rhythm leads to increased oxidative stress resulting in the nuclear translocation of Nrf2, where it binds to the ARE initiating the transcription of several cytoprotective genes

6.1.4 Gut microbiome and ferroptosis Recently, the pathophysiology of IBD has been linked to the adherent-invasive Escherichia coli (AIEC) pathotype of E

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Available from: /pmc/articles/PMC9604961/ 588

doi: 10.3390/ijms231810665 102
