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Proc Natl Acad Sci U S A 117(33):19982-93 2020 PMC7443878 Shao B, Mathew AV, Thornock C, Pennathur S, Michigan Kidney Translational Core CPROBE Investigator Group

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Amino acid sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH Molecular weight: ~1025.18 Da (one water molecule heavier due to ring opening) Molecular formula: C50H71N15O10 Number of amino acids: 7 (with N-terminal acetylation, free C-terminal acid) Cyclization: None linear peptide Key difference from MT-II: Lactam bridge hydrolyzed

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Like a trusty little molecule transporting fatty acids to their energy-burning destination , we've transported you through the ins and outs of this amazing compound

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10.2147/DDDT.S49763

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