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Description
Several analogs exhibited more potent cytotoxicity against HeLa cells compared to 381, including those containing meta -halogenation in the supplied 382 mimics
This is the exploratory phase
The result is controlled, localised, and short-term loss of sensation without affecting mental alertness.

Ebright RY, Lee S, Wittner BS, Niederhoffer KL, Nicholson BT, Bardia A, et al

Lancet Diabetes Endocrinol 5: 134-142

M., Mukhopadhyay P., Matyas C., Trojnar E., Damadzic R., et al
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