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E.Hernandez-SapiensM

Drug Deliv Transl Res [Internet]

Safety & Tolerability BPC-157 : Preclinical animal studies suggest high tolerability, no significant systemic toxicity reported

In contrast to other MYC family transcription factors, MYCN is expressed exclusively during embryogenesis and only in specific cell types (such as pre-B cells, kidney, forebrain, hindbrain, and intestinal cells) 10

This treatment is not FDA-approved for any specific medical condition

Recently, the retinoblastoma protein (Rb) was found to suppress ferroptosis in response to sorafenib [30], suggesting that Rb status may aid in selecting ferroptosis-sensitive tumors, at least for sorafenib