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They establish plausibility and a direction of effect

What vitamin b is biotin

If you have been on long term medication like omeprazole or lansoprazole, have had a poor diet or are vegan/vegetarian you may benefit from having a course of Vitamin B12 Injections

Gao, Xy., Hou, F., Zhang, Zp

A recent systematic review and meta-analysis of 21 randomized, placebo-controlled trials examining the effect of B-vitamin supplementation found the supplementation decreased homocysteine concentrations and improved measures global cognitive function but had no effect on individual measures of executive function, information processing speed, or episodic memory (89)
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