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doi: 10.1002/jcp.21626
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Humoral factors in ALS patients during disease progression
[DOI: 10.1016/S2665-9913(20)30121-1] [DOI] [PMC free article] [PubMed] [Google Scholar] 16.Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Taylor Thompson B, Marco Ranieri V
Thus, removal of the C-terminal L585 reduces the ability of the albumin fusions to engage human FcRn, and thereby compromises their rescue from intracellular lysosomal degradation
This is where glutathione becomes a hero rather than a culprit
