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This reduction correlated with impaired motor function and the development of compulsive drug-seeking behaviors ( MRI studies have further identified gray matter atrophy in the prefrontal cortex, medial cingulate gyrus, and hippocampus, regions that are critically involved in memory, decision-making, and emotional regulation ( Magnetic resonance spectroscopy provides complementary biochemical evidence of METH-induced neurotoxicity

2023 Apr 11;28(8):3375

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If a dose is missed, patients could apply it when remembered on the same day or resume the regular schedule at the next planned administration-double dosing is not recommended

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