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Self-reported quality-of-life (QoL) measures also highlight fatigue as a key problem in hypothyroidism (29)

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While previous research has primarily explored the biochemical alterations stemming from the defective pathways directly linked to VitB12 as a coenzyme, the investigation of secondary alterations involving molecular changes and cellular alterations is a more recent focus

doi: 10.1007/s13311-014-0329-3

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Similarly, elevated levels of carboxyhemoglobin may protect against inflammatory injury during reperfusion in marine mammals despite detracting from the overall oxygen-binding capacity of the blood (Otterbein et al., 2000