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Hypoxia may promote cancer growth by inhibiting ferroptosis, which causes difficulties in cancer treatment

Blood 2002;99:29973004

Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

Moreover, AGEs promote the aging of TSPCs, reducing their regenerative potential [60]

Badenhorst T, Svirskis D, Merrilees M, Bolke L, Wu Z (2016) Effects of GHK-Cu on MMP and TIMP expression, collagen and elastin production, and facial wrinkle parameters

Multiple reviews have explored these structural features and physiological roles in detail 2,2125 and this perspective will focus on the most recent findings