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For type 2 diabetes management, the medication may be needed long-term as diabetes is a chronic condition requiring ongoing treatment, though some patients may be able to reduce or discontinue medication if significant weight loss and lifestyle modifications lead to remission of their diabetes

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The meeF-meeY (FY) mutant strain can be rescued by induction of the expression of FtsH, an ATP-dependent metalloprotease that is known to clear jammed SecYEG translocons (Figure 58, left )

Animal housing and feeding were centrally managed by the UNC Division of Comparative Medicine

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