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Increased MPO activity in testicular tissue could be linked to neutrophil activation brought on by an excess of ROS

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Various enzyme systems such as cytochrome P450, the mitochondrial respiratory chain, xanthine oxidase (XO), uncoupled endothelial nitric oxide synthase (eNOS), heme oxygenase (HO), myeloperoxidase (MPO), lipoxygenase (LOX), cyclooxygenase (COX) and NADPH oxidases (NOX) generate ROS especially in a pathological state [51]

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Medicine 103 , e37360 (2024)