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Moreover, a computational simulation study predicted that curcumin is a potent competitive GST inhibitor and proposed a combination usage with chemotherapeutic agents for an improved efficacy [151]

Heres the caveat: while the animal data is overwhelmingly positive, human studies are extremely limited

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Downregulation Downregulation specifically refers to a reduction in the total number of receptors available to be stimulated due to prolonged receptor activation (e.g

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doi: 10.1074/jbc.270.3.995