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B12 deficiency can also lead to the destruction of immature red blood cells in the bone marrow, which can cause jaundice (yellowing of the skin and whites of the eyes)

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Our guide on water types for peptide reconstitution covers this distinction in detail

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Alternatively, the diagnostic criteria used to identify inadequate B12 status have been based on a known relationship between the serum B12 biomarker and low body stores, functional impairment, or clinical signs of deficiency
