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The GutKidney Axis

the composition, so administered may be regarded either as a food additive, a substance that is generally regarded as safe (i.e., a GRAS substance), or a drug within the meaning of Title 21 of the Code of Federal Regulations (CFR)

A growing body of data implicates 4-HNE is an important effector or biomarker of oxidative stress [65]

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It also explains how and for what purpose this is done

[DOI] [PubMed] [Google Scholar] 39.Charach G, Rabinovich A, Argov O, Weintraub M, Rabinovich P