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Previous studies have demonstrated that hydrogen gas can inhibit the formation of nitrotyrosine (Zhang et al., 2016), a detectable marker for the indirect measurement of ONOO (Wu et al., 2018), suggesting that hydrogen gas may exert its antioxidant effects by inhibiting ONOO

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The proposed mechanisms of action and therapeutic benefits of synthetic ATs are summarized in Table 4

is funded by NIH K99 DK128602-01