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Nutritional monitoring should be more frequent, every 3 months, since reduced appetite combined with age-related absorption changes increases deficiency risk

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Am J Physiol 276(5):R1541R1544 Henness S, Keam SJ (2006) Vildagliptin Drugs 66:19892001 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB et al (2017) Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

Retatrutide has a six-day half-life, which means partial therapeutic levels persist even when a dose is missed, but consistency is important for steady adaptation during the starting period