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Furthermore, comparative investigations help support organized research methodologies and repeatable laboratory workflows

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494,495 Subsequent multi-center studies also demonstrated high rates of complete and durable response in advanced melanoma patients administrated with T-VEC, 496,497 even for the local lesions of patients who developed acquired resistance to immune checkpoint blockade

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Telomere shortening leads to cellular senescence, which is associated with the activation of the p16INK4a/Rb signaling pathway that inhibits cell cycle progression