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[DOI] [PMC free article] [PubMed] [Google Scholar] 539

Can lead to severe osteoarthritis if not managed

Similarly, the class I HDAC inhibitor SAHA, but not a class II HDAC inhibitor, increases the expression of PGC-1 thus leading to enhanced mitochondrial biogenesis, oxygen consumption in adipose tissue and skeletal muscle from mice with type 2 diabetes (174)
This compound is utilized in controlled scientific settings for the study of molecular chemistry, structure-function relationships, and biochemical characteristics under experimental conditions

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