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Description
It is eliminated rapidly by the kidney and only metabolized to the extent of 10-15%, which suggests that effects are due to the parent compound

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thereby prolonging the ability to live independently

often CYP3A4-dependent

642,643 These results suggest that NNMT is an appealing target for obesity and type 2 diabetes treatment

To avoid a potential risk of hypercobalaminemia or possible health risks of high-dose dietary supplements, an annual blood test is recommended, after which targeted substitution can be performed
