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Proposed mechanisms include the following
Muscle-organ crosstalk: the emerging roles of myokines
R.FruscianteL.ChiusanoM
Shah, D., Aggarwal, A., Bhatnagar, A., Kiran, R., & Wanchu, A
doi: 10.1016/j.pnpbp.2018.09.011 196 MondelliVBlackmanGKemptonMJPollakTAIyegbeCValmaggiaLRet al
The IGF Signaling Pathway in Breast Cancer Expression of the ligands, receptors, and adaptor proteins of the IGF signaling pathway are altered in breast cancer, often in a subtype-dependent manner, leading to enhanced activity
