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PubMed Central , Environmental Health , vol

Vet Rec 2012;170:179-184

The result of mitochondrial dysfunction includes excess ROS generation, altered energy production, and impaired calcium buffering

meaning that riboflavin deficiency can cause increased glutamate and deceased GABA levels, thereby contributing to excitotoxicity
Neither trial reported adverse effects
Grinspan's syndrome: a drug-induced phenomenon
