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Funding This work has been funded by the Spanish Society of Nephrology (Grant for Research in Nephrology, 2021) and it is submitted as a benefit for this grant

An alternative approach to improving therapeutic outcomes is to combine ICB with other treatments (Rotte, 2019)

Some radioprotective agents can be found in high quantities in antioxidant rich foods, suggesting that a specific diet recommendation could be beneficial in radioprotection

The R1 group of 16 was held tightly by two additional hydrogen bonds engaging the side chain of H64 from a neighboring protease protomer (C) and the backbone carbonyl of P168, in addition to a - interaction between the triazole ring of 16 and F305 of protomer B (Fig