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Abstract Skeletal muscle wasting, associated with aging, may be regulated by the inflammatory cytokines as well as by insulin-like growth factor 1 (IGF-1)
The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice
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Mitochondria dysfunction in the pathogenesis of Alzheimers disease: Recent advances

This randomized, double-blind, placebo-controlled trial in 58 older adults identified as "pre-frail" found an decrease in a Frailty Index score and an improvement in the hand grip test in individuals supplemented with L-carnitine (1.5 g/day) over 10 weeks but not in those given a placebo (118)

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