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As a final consideration in defining the causative factors that contribute to increased OS in maternally aged oocytes, it is notable that the oxidative defence capacity of surrounding granulosa and cumulus cells have also been reported to decline with age 102,103,104

T-cells play an important role in recognizing foreign pathogens and destroying them, as well as other roles like regulating and remembering immune responses

It induces apoptosis in malignant cells by upregulating p27kip1 and Caspase-3, acting as a "smart" molecule that supports healthy cells while targeting damaged ones

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