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A study by Adham et al
JNK An early result of APAP-induced mitochondrial oxidative stress is the activation of JNK in the cytoplasm
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Cell 164 , 681694 (2016)
Turgeon ML
Interferon and high dose IL-2 are the earliest immunotherapies clinically used to treat various malignant tumors, whereas new cancer immunotherapies have emerged in the past decade, such as the above-mentioned immune checkpoint inhibitors that activate quiescent T cells and impair the ability of tumors to turn off activated T cells in the tumor microenvironment
