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None of the above inclusion criteria or exclusion criteria affected the experimental results

Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition

The oxidative stress caused by a decrease in GSH levels can then impact microglia function and potentially lead to a more pro-inflammatory M1 phenotype that has reduced -amyloid clearance capabilities (Vilhardt et al., 2017)

Replacing asparagine with glutamine at the 8th position might potentially reduce the risk of asparagine rearrangement and amide hydrolysis

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The Diversity in Physiological Functions of Free Glutamine and Glutamate In the last decade, it has been recognized that glutamine and glutamate are essential AAs at key times in life, including the neonatal period when rapid growth occurs (78, 79)