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It is very soluble in water, ethanol and methanol, slightly soluble in acetone, but insoluble in ether, benzene, chloroform and ethyl acetate
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In addition to blocking coactivator binding, H12 repositioning allows the recruitment of corepressors such as nuclear receptor co-repressor 1 (NCoR) and silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) (PDB: 1KKQ) (Figure 4D) 93

Whitt JC, Jennings DR, Arendt DM, et al