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PC9 or PC9ER cells were injected subcutaneously in nude mice and tumours were left to grow to 100 mm 3

M.KllB.BirimD.Kaftan calG.DacT.et al (2024)

Although serious adverse effects are rare, the incidence of minor adverse events may be considerable

However, it is hypothesized that after birth, the iodine-deficient thyroid gland, which is hyperplastic and hyperstimulated, generates an excess of free oxygen radicals that, in addition to reduced GPx activity, could trigger the destruction of the thyroid gland

Many compounds that produce extraordinary results in preclinical models fail to replicate those outcomes in human clinical trials
