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However, this Wilson disease cohort was heterogeneous, as it included patients receiving D-penicillamine or zinc sulfate, which may have confounded the results [57]

The voxel sizes for the SN region 30 35 25 mm 3 (tissue volume 26.2 cm 3 ) and the left hippocampal region 25 25 25 mm 3 (tissue volume 15.6 cm 3 ) are taken in our study

However, others may progress to overt hypothyroidism if thyroidal reserve is limited and metabolic demands are high

To explore the cellular consequences downstream of insulin-activated ATM, quantitative label-free phosphoproteomics analysis was performed in cerebellar tissues collected from both Atm -WT and Atm -KO mice, which identified a total of 2320 phosphosites that could be reproducibly quantified (Supplementary Dataset 1)

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