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Researchers should match their analytical approach to the specific demands of their study, whether that means deploying HPLC-MS/MS for precise GSH/GSSG quantification, using genetically encoded biosensors like roGFP2-Grx1 for real-time subcellular redox mapping, or leveraging high-throughput fluorescent assays for large-scale screening campaigns

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Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB
