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It may be pertinent for clinicians to check carnitine levels with other routine diet therapy lab monitoring (at 3 months, 6 months, then every 6 months) since patients are often asymptomatic, and carnitine deficiency may go undetected if it is not checked

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It seems to be able to cross the blood brain barrier (BBB) and neuronal membranes to enhance cognitive function and reduce neurological decline

However, when the level of long-chain acylcarnitines (LCACs) is abnormally elevated, not only is it a signal of mitochondrial dysfunction but its high concentration can also aggravate mitochondrial damage and further deteriorate mitochondrial function [20, 21]