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Introduction Major depressive disorder (MDD) is one of the most common psychiatric disorders and is characterized by marked mood swings with sadness or irritability and psychophysiological changes such as sleep, appetite, and libido disturbances lasting for at least 2 weeks ( Metabolomics is the study of small molecules (up to 1.5 kDa) called metabolites

Raja Gopal Reddy et al., 2016

Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury

De Filippis B, Valenti D, de Bari L, De Rasmo D, Musto M, Fabbri A, et al

In addition, the researchers propose, other factors also may contribute, such as certain medications, minor illnesses (especially gastrointestinal conditions) and perhaps changes in the microbiome that might deplete carnitine from the body
