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This can be explained by methylcobalamins role as acofactor in myelin synthesis
The extracts of these mushrooms include chemicals such as phenolics, flavonoids, polysaccharides (particularly -glucans), terpenoids, sterols, and lectins, which display substantial anti-inflammatory, antioxidant, immunomodulatory, and anticancer properties
In rodent models of CIPN, volitional wheel running reduced both the development and the maintenance of cold and mechanical allodynia

BDNF promotes the survival and maturation of dopaminergic neurons, which are crucial in PD pathology

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Animal models have played an essential role in advancing our understanding of periodontitis pathogenesis and in developing preventive and therapeutic strategies [10, 64, 66, 67, 68]
