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10.1007/s00018-016-2268-0 17 LiY.ZhuH.WeiX.LiH.YuZ.ZhangH.et al (2017)

BPC-157 initiates the repair signal
It was more effective in reducing NO production than celecoxib and diclofenac, with equivalent TNF- inhibition to diclofenac

Not only does the resulting barrier disruption promote diarrhoea because of increased water concentration in the intestinal lumen, but there is also a greater opportunity for the development of secondary infections due to deeper tissue penetration by other pathogens and toxins (Guttman and Finlay 2009)

For individuals dealing with chronic pain that interferes with sleep, DSIP's combined analgesic and sleep-promoting effects could be particularly relevant

Some clinicians also use calming peptides in broader plans, like Selank, but that still needs clinician screening
