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Unexpectedly, subjects receiving CNTF in clinical trials for this indication experienced weight losses of 10--15%, prompting researchers to consider using CNTF to treat obesity [71]

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OVERALL CONCLUSIONS 5-Amino-1MQ enables precise interrogation of NNMTs role at the crossroads of NAD metabolism, one-carbon biochemistry, and adipocyte energetics

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[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Aguree S., Murray-Kolb L.E., Diaz F., Gernand A.D