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Any disagreements were resolved through a discussion within the entire review team

During lipid peroxidation, cyclic guanosine monophosphate (cGMP) is elevated, along with the downregulation of cyclic adenosine monophosphate (cAMP) concentration, leading to accelerated proliferation of epidermal cells in psoriasis ( Extensive experiments are proving that various subsets of T cells, including Th1, Th2, Th17, and regulatory T cells (Treg cell), as well as related cytokines, such as TNF-, IFN-, IL-23, and IL-17, engage in the pathogenesis of psoriasis (Soler et al., 2013

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doi: 10.1371/journal.pcbi.1013504, [DOI] [PMC free article] [PubMed] [Google Scholar] Peek C

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