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The Kennedy Center

[133] evaluated the use of metformin (10002000 mg/die) in six RCTs (573 individuals treated for a median of 9 months

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is developing HGF mimetics and antagonists for the treatment of various disorders including dementia

This work was supported in part by a KAKENHI grant from the Japan Society for the Promotion of Science [grant numbers 23K13883] (M.M.) and the Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP24ama121054 (M.A.)