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Certain brain disorders have accelerated neuro-degeneration that give us clues

J Thorac Oncol

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Studies have shown that increasing antioxidant levels, specifically glutathione, may support improved sperm motility and overall concentration
Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis

At the same time, elevated tumor GSH can be exploited as a conditional trigger for prodrug activation, nanomedicine-based delivery, or metal-driven cytotoxicity, thereby converting a classical resistance factor into a therapeutically actionable vulnerability
