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The endothelial damage, release of TF and intravascular TF, and elevated proinflammatory cytokines trigger immunothrombosis in the pulmonary microvasculature, yielding microclots [15]

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These proteins are involved in the regulation of inflammation and immune response and form the calprotectin heterodimer (S100A8/A9) [122]

H., Caldwell, J., Jamieson, L., Orr, E., and Mochly-Rosen, D

Ji Q, Zhang L, Jia H, Xu J

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