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From nine rats of each group, gingivomucosal tissue samples were collected from both the ligature and the non-ligature contralateral sides and vascular permeability was measured as described in Materials and Methods

Additional analysis explored the interaction between BPC 157 and several neurotransmitter and signaling systems, including dopaminergic, nitric oxide, prostaglandin, and somatosensory pathways

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In addition, BPC 157 could promote VEGFR2 internalization in vascular endothelial cells which was blocked in the presence of dynasore, an inhibitor of endocytosis