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Sotatercept for Anemia of Myelofibrosis: a Phase 2 Investigator-initiated

To view a copy of this licence, visit About this article Cite this article Kim, S., Pack, S.P

10.1017/S000711452000210X 151

Polymorphisms in genes like MTHFR or autoantibodies against folate receptor alpha (FR) obstruct cerebral folate transport , compounding the neurological burden

Increased GSH synthesis neutralizes reactive oxygen and nitrogen species and regulates zinc homeostasis promoting neuroprotection after ischemia/reperfusion (162)

In summary, renal inflammation, oxidative stress, and programmed cell death often coexist during the development of GN kidney injury
