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Vitamin B12 deficiency symptoms range from mild and easily overlooked to severe and potentially irreversible

Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting

This is less common now with food fortification

There is no clinical science, and the basic science is remarkably alarming

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